Submerging Endoscopic Submucosal Dissection Leads to Successful En Bloc Resection of Colonic Laterally Spreading Tumor with Submucosal Fat

A 72-year-old female with a colonic laterally spreading tumor (LST) was referred to our department.A total colonoscopy revealed a large nongranular LST, 30 mm in diameter, in the ascending colon.Detailed examination with chromoendoscopy confirmed that the lesion was an intramucosal tumor, and endoscopic submucosal dissection (ESD) was performed.Aft

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Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition

Nucleoplasmin (Npm) is an abundant histone chaperone in vertebrate oocytes and embryos.During embryogenesis, regulation of Npm histone binding is critical for its function in storing and releasing maternal histones to establish and maintain the zygotic sensationnel kiyari epigenome.Here, we demonstrate that Xenopus laevis Npm post-translational mod

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Evaluation of in-house loop-mediated isothermal amplification for tuberculosis diagnosis compared with Xpert MTB/RIF

Introduction: To evaluate the diagnostic performances of an in-house loop-mediated isothermal amplification (LAMP) kit and the Xpert MTB/RIF test for the diagnosis of pulmonary tuberculosis in a resource-limited setting, this study was performed at the University Teaching Hospital, Ministry of Health, the Republic of Zambia.Methodology: Two hundred

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